Author Contributions: Drs Gu and He had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Drs Gu and He contributed equally to this work.
Study concept and design: Gu, He, Wu, J. Chen, Whelton.
Acquisition of data: Gu, He, Duan, Wu, Huang, Whelton.
Analysis and interpretation of data: Gu, He, Reynolds, J. Chen, C.-S. Chen, Whelton.
Drafting of the manuscript: He.
Critical revision of the manuscript for important intellectual content: Gu, He, Duan, Reynolds, Wu, J. Chen, Huang, C.-S. Chen, Whelton.
Statistical analysis: He, Reynolds, C.-S. Chen.
Obtained funding: Gu, He.
Administrative, technical, or material support: Gu, He, Whelton.
Study supervision: Gu, He.
Financial Disclosures: None reported.
Funding/Support: This study was supported by national grant-in-aid 9750612N from the American Heart Association and partially supported by grant U01 HL072507 from the National Heart, Lung, and Blood Institute of the National Institutes of Health and grant 1999-272 from the Chinese Ministry of Health and the Chinese Academy of Medical Sciences.
Role of the Sponsor: The sponsors did not play any role in the design and conduct of the study, in the collection, management, analysis, or interpretation of the data, or in the preparation, review, or approval of the manuscript.
Steering Committee Members: Jiang He (coprincipal investigator), Dongfeng Gu (coprincipal investigator), Jing Chen, Rutai Hui, Michael J. Klag, Lingzhi Kong, Shouqi Tao, Jialiang Wang, Paul K. Whelton, Xigui Wu, and Chonghua Yao.
Participating Institutes and Principal Staff:United States: Tulane University Health Sciences Center, New Orleans, La: Chung-Shiuan Chen, Jing Chen, Jiang He, Kristi Reynolds, Paul K. Whelton, Rachel P. Wildman, C. Lillian Yau; Johns Hopkins Bloomberg School of Public Health, Baltimore, Md: Michael J. Klag; China: Fu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing: Tianxiu Cao, Xiufeng Duan, Wenqi Gan, Dongfeng Gu, Guangyong Huang, Shouqi Tao, Xigui Wu, Wenjie Yang, Jiangong Zhao; Chinese Ministry of Health, Beijing: Lingzhi Kong; Tianjin City Bureau of Public Health, Tianjin: Gengwen Zheng; Tianjin City Center of Diseases Control and Prevention, Tianjin: Guide Song; Guangdong Provincial People's Hospital and Cardiovascular Institute, Guangdong: Xiaoqing Liu, Jinzhuang Mai; Anzhen Hospital, Capital University of Medical Sciences and Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing: Chonghua Yao; Capital Iron and Steel Company's Hospital, Beijing: Xuehai Yu; Fangshan District Hospital, Beijing: Xisheng Xu; Zhejiang Provincial Center for Cardiovascular Disease Prevention and Research, Zhejiang: Hongyi Jin, Xinhua Tang; Fujian Provincial People's Hospital, Fujian: Xiaodong Pu, Ling Yu; Shandong Provincial Academy of Medical Sciences, Shandong: Shantong Zhang; Guangxi Medical University, Guangxi: Liguang Zhu; Xi’an Jiaotong University Medical School, Shanxi: Jianjun Mo; Henan Provincial Academy of Medical Sciences, Henan: Jinling Guo; Tongji Medical College and School of Public Health, Huazhong University of Science and Technology, Hubei: Yuzhi Hu, Yizhen Yu; Sichuan Provincial Center of Diseases Control and Prevention, Sichuan: Xianping Wu; West China College of Medicine, Sichuan University, Sichuan: Jialiang Wang; Nanjing Medical University, Jiangsu: Hongbing Shen, Cailiang Yao; Beihua University Medical School, Jilin: Lihua Xu, Guijiang Zhao; Inner Mongolia Hospital, Inner Mongolia: Xuewen Gao, Jingchun Zhou; First Clinical College of Harbin Medical University, Heilongjiang: Yaoping Li; Daqing City Center of Diseases Control and Prevention, Heilongjiang: Zhenyi Li; Hebei Provincial Academy of Medical Sciences, Hebei: Hongxiu Zhang; and Zhongshan Hospital and Institute of Cardiovascular Diseases, Fudan University, Shanghai: Xinwei Pan.