Author Contributions: Dr Taddio had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Taddio, Shah.
Acquisition of data: Taddio, Lee, Yip, Parvez, McNamara, Shah.
Analysis and interpretation of data: Taddio, Lee, Yip, Parvez, McNamara, Shah.
Drafting of the manuscript: Taddio, Shah.
Critical revision of the manuscript for important intellectual content: Taddio, Lee, Yip, Parvez, McNamara, Shah.
Statistical analysis: Taddio, Lee, Yip, Shah.
Obtained funding: Taddio, Shah.
Administrative, technical, or material support: Taddio, Shah.
Study supervision: Taddio, Parvez, McNamara, Shah.
Financial Disclosures: None reported.
Funding/Support: Funding for this study was provided by the Canadian Society of Hospital Pharmacists. Dr Taddio is supported by the Canadian Institutes of Health Research New Investigator Award. Ms Lee was supported through a studentship by the Ontario Student Opportunity Trust Fund–Hospital for Sick Children Foundation Student Scholarship Program.
Role of the Sponsor: The funding agencies had no input in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, and approval of the manuscript.
Acknowledgment: We are grateful to Derek Stephens, MSc, and Eshetu Atenafu, MSc, for their assistance with the statistical analyses and Lucia Taddio, BA, Erwin Darra, and Omar Parvez for their assistance with data collection (all from The Hospital for Sick Children); and to the staff of the neonatal intensive care units of The Hospital for Sick Children and Mount Sinai Hospital and parents of participating neonates for their support of the study. We also thank Gideon Koren, MD (The Hospital for Sick Children) and Arne Ohlsson, MD (Mount Sinai Hospital) for their guidance during the trial. Ms Taddio and Mr Darra received compensation from the study sponsor.