Author Contributions: Dr Chen had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Chen, Yang, Su, Huang, Iloeje.
Acquisition of data: Chen, Yang, Jen, You, Lu, Huang.
Analysis and interpretation of data: Chen, Yang, Su, Iloeje.
Drafting of the manuscript: Chen, Iloeje.
Critical revision of the manuscript for important intellectual content: Chen, Yang, Su, Jen, You, Lu, Huang, Iloeje.
Statistical analysis: Yang, Su, Iloeje.
Obtained funding: Chen, Su, Iloeje.
Administrative, technical, or material support: Chen, Yang, Jen, You, Lu, Huang.
Study supervision: Chen.
Financial Disclosures: None reported.
Funding/Support: Dr Chen received a grant from Bristol-Myers Squibb to conduct the laboratory tests for this study. This study also was supported by the Department of Health, Executive Yuan, Republic of China.
Role of the Sponsor: Drs Iloeje and Su (employed by Bristol-Myers Squibb) were involved in the study design, development of the analysis plan, and interpretation of the data and writing of the manuscript. All data handling and statistical analyses were done by the staff at the National Taiwan University. At no time did the funding sources have access to the data.
Other Members of the REVEAL-HBV Study Group:National Taiwan University Hospital: C. Y. Hsieh, H. S. Lee, P. M. Yang, C. H. Chen, J. D. Chen, S. P. Huang, C. F. Jan. National Taiwan University: T. H. H. Chen. National Defense Medical Center: C. A. Sun. Taipei City Psychiatric Center: M. H. Wu. Tzu Chi University: L. Y. Wang, S. Y. Chen. Shin Kong Wu Ho-Su Memorial Hospital: K. E. Chu. Huhsi Health Center, Penghu County: S. C. Ho, T. G. Lu. Provincial Penghu Hospital: W. P. Wu, T. Y. Ou. Sanchi Health Center, Taipei County: C. G. Lin. Provincial Chutung Hospital: K. C. Shih. Provincial Potzu Hospital: W. S. Chung, C. Li. Kaohsu Health Center, Pingtung County: C. C. Chen. Paihsa Health Center, Penghu County: W. C. How.
Acknowledgment: We thank Yun-Fan Liaw, MD, of the Chang-Gung Memorial Hospital and University (Taipei, Taiwan) for his very helpful comments and suggestions.