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Comment & Response |

Colorectal Cancer and the Effect of Flexible Sigmoidoscopy Screening—Reply

Øyvind Holme, MD1; Magnus Loberg, MD1; Mette Kalager, MD, PhD1
[+] Author Affiliations
1Institute of Health and Society, University of Oslo, Oslo, Norway
JAMA. 2014;312(22):2411-2412. doi:10.1001/jama.2014.14695.
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In Reply Dr Swartz is concerned because the effect estimates reported in our study were standardized by age group (classified as 50-54 vs 55-64 years) and because previously published articles from the Norwegian Colorectal Cancer Prevention (NORCCAP) trial did not standardize for age.

Previous articles included only the 55- to 64-year age group (or only the screening group) and therefore had no need to consider this issue. Our article is the first to report results for the 50- to 54-year-old age group (including the control group), and therefore we had to consider the different age distribution between the screening and control groups in the analysis.


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December 10, 2014
Andrew W. Swartz, MD
1Yukon Kuskokwim Health Corporation, Bethel, Alaska
JAMA. 2014;312(22):2411. doi:10.1001/jama.2014.14692.
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