Genomics and neuroscience, 2 areas of science fundamental to psychiatry, have undergone revolutionary changes in the past 20 years. Yet methods of diagnosis and treatment for patients with mental disorders have remained relatively unchanged. Indeed, during the same time, the public health burden of mental disorders has grown alarmingly. Mental disorders are now among the largest sources of medical disability worldwide1 and, like AIDS and cancer, they are urgent and deadly.2,3
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