Targeted cognitive behavioral therapy (CBT) may improve negative symptoms, such as a lack of motivation, in severely impaired patients with schizophrenia, new findings suggest.
Most treatments for schizophrenia target the positive symptoms of the disorder, such as hallucinations and delusions. Yet negative symptoms of the disorder, such as a lack of motivation and deficits in cognition and language, are often the most disabling for patients.
A team of researchers recently conducted a single-center randomized trial to see if CBT focusing on reducing fear of failure and patients' efforts to avoid failure could improve functioning in patients with schizophrenia. The 60 trial participants had difficulties with information processing related to memory, attention, and executive functioning, as well as residual positive symptoms despite treatment. These severely impaired patients were randomly assigned to receive either 18 months of standard treatment (usually involving medication) or 18 months of standard treatment plus CBT (Grant PM et al. Arch Gen Psychiatry. doi: 10.1001/archgenpsychiatry.2011.129 [published online ahead of print October 3, 2011]).
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 1
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Care at the Close of Life EDUCATION GUIDES
Caring for Bereaved Patients
All results at
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.