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Biomarkers for Detecting and Risk-Stratifying Chronic Kidney Disease

Lei Zhao, MD; Wei Wang, MD; Yan Cui, MD
JAMA. 2011;306(6):611-612. doi:10.1001/jama.2011.1111.
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To the Editor: Dr Peralta and colleagues1 reported that “adding cystatin C to creatinine and albuminuria for risk prediction can more accurately reclassify persons and can distinguish important prognostic differences, namely a 3-fold risk of death and 4-fold risk of end-stage renal disease.” However, they did not explain why they chose cystatin C as a biomarker for CKD diagnosis or assess the accuracy of applying it.

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References

August 10, 2011
Peter J. Fabri, MD, PhD
JAMA. 2011;306(6):611-612. doi:10.1001/jama.2011.1110.
August 10, 2011
Carmen A. Peralta, MD, MAS; Michael G. Shlipak, MD, MPH
JAMA. 2011;306(6):611-612. doi:10.1001/jama.2011.1112.
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