Author Contributions: Dr Berkley had full access
to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design: Berkley, English,
Acquisition of data: Berkley, Mwangi, Griffiths,
Ahmed, Mithwani, English, Maitland.
Analysis and interpretation of data: Berkley,
Drafting of the manuscript: Berkley, Ahmed,
Critical revision of the manuscript for important
intellectual content: Berkley, Mwangi, Griffiths, Mithwani, English,
Statistical analysis: Berkley, Mithwani, Maitland.
Obtained funding: Berkley.
Administrative, technical, or material support:
Griffiths, Mithwani, English.
Study supervision: Mithwani, English, Newton,
Financial Disclosures: None reported.
Funding/Support: This study was supported by
the Wellcome Trust. Dr Berkley was a Wellcome Trust Training Fellow in Clinical
Tropical Medicine (053439), Dr Newton is a Wellcome Trust Senior Clinical
Fellow (050533), and Dr English is a Wellcome Trust Career Development Fellow
Role of the Sponsors: The Kenya Medical Research
Institute (KEMRI) and the Wellcome Trust had no role in the design and conduct
of the study; the collection, management, analysis, and interpretation of
the data; or the preparation, review, or approval of the manuscript. This
article is published with the permission of the director of KEMRI.
Acknowledgment: We thank the Medical Officer
of Health, the Medical Superintendent, the staff of Kilifi District Hospital,
and Norbert Peshu, MPH, Kenya Medical Research Institute Centre for Geographic
Medicine Research (coast), for their support. We are grateful to all the KEMRI
and nursing staff for their assistance. We also thank Steven Allen, PhD, Department
of Paediatrics, University of Wales Swansea, for his helpful advice.