Author Contributions: All of the authors had
full access to all of the data in the study and take responsibility for the
integrity of the data and the accuracy of the data analysis.
Study concept and design: Babaev, Hochman.
Acquisition of data: Babaev, Sichrovsky.
Analysis and interpretation of data: Babaev,
Frederick, Pasta, Every, Sichrovsky, Hochman.
Drafting of the manuscript: Babaev, Sichrovsky.
Critical revision of the manuscript for important
intellectual content: Babaev, Frederick, Pasta, Every, Hochman.
Statistical analysis: Frederick, Pasta, Every.
Obtained funding: Every.
Administrative, technical, or material support:
Babaev, Sichrovsky, Hochman.
Study supervision: Hochman.
Financial Disclosures: None reported.
Funding/Support: Genentech Inc provided funding
for the data management and statistical analysis.
Role of the Sponsor: Genentech Inc was not
involved in the analysis of this study other than providing funds for data
management and statistical analysis.