Author Contributions: Dr van Dam had full access
to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design: van Dam, Hu.
Acquisition of data: van Dam.
Analysis and interpretation of data: van Dam,
Drafting of the manuscript: van Dam.
Critical revision of the manuscript for important
intellectual content: van Dam, Hu.
Statistical analysis: van Dam.
Obtained funding: van Dam, Hu.
Administrative, technical, or material support:
Study supervision: Hu.
Financial Disclosures: None reported.
Funding/Support: This work was supported by
NIH research grant DK58845. Dr van Dam is partly supported by the Netherlands
Organization for Scientific Research (ZonMw VENI grant 916.46.077). Dr Hu
is partly supported by an American Heart Association Established Investigator
Role of the Sponsors: The funding agencies had
no role in the design and conduct of the study; in the collection, management,
analysis, and interpretation of the data; or in the preparation, review, or
approval of the manuscript.