Author Contributions: Dr Coresh had full access
to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design: Hsu, Kao, Coresh.
Acquisition of data: Coresh, Boerwinkle, Bray.
Analysis and interpretation of data: Hsu, Kao,
Coresh, Pankow, Marsh-Manzi.
Drafting of the manuscript: Hsu.
Critical revision of the manuscript for important
intellectual content: Hsu, Kao, Coresh, Pankow, Marsh-Manzi, Boerwinkle,
Statistical analysis: Hsu, Kao, Marsh-Manzi.
Obtained funding: Hsu, Coresh, Marsh-Manzi,
Administrative, technical, or material support:
Kao, Coresh, Pankow, Boerwinkle, Bray.
Study supervision: Kao, Coresh.
Financial Disclosures: None reported.
Funding/Support: The Atherosclerosis Risk in
Communities Study was supported by contracts N01-HC-55015, N01-HC-55016, N01-HC-55018,
N01-HC-55019, N01-HC-55020, N01-HC-55021, and N01-HC-55022 with the National
Heart, Lung, and Blood Institute. This work was also supported by National
Institutes of Health grant HL73366 and the Centers for Disease Control and
Prevention grant UR6/CCU617218 (Dr Bray), grant 5T32HL007024 (Dr Marsh-Manzi),
the Medical Scientist Training Program (Dr Hsu), the American Diabetes Association
Medical Scholars Award (Dr Hsu), and the American Heart Association Established
Investigator Award 01-4019-7N (Dr Coresh).
Role of the Sponsors: Except NHLBI input through
the ARIC contract, the organizations funding this study had no role in the
design and conduct of this study; the analysis and interpretation of the data;
or the preparation, review, or approval of the manuscript.
Acknowledgment: We are indebted to the staff
and participants in the Atherosclerosis Risk in Communities Study for their