Author Contributions: Dr Grant had full access
to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design: Grant, Corbett, Chaisson,
De Cock, Hayes, Churchyard.
Acquisition of data: Grant, Charalambous, Day,
Analysis and interpretation of data: Grant,
Fielding, De Cock, Hayes, Churchyard.
Drafting of the manuscript: Grant, Churchyard.
Critical revision of the manuscript for important
intellectual content: Grant, Charalambous, Fielding, Day, Corbett,
Chaisson, De Cock, Hayes, Churchyard.
Statistical analysis: Grant, Fielding, Hayes.
Obtained funding: Grant, Churchyard.
Administrative, technical, or material support:
Grant, Charalambous, Day, Corbett, Chaisson, Churchyard.
Study supervision: Grant, Hayes.
Financial Disclosures: None reported.
Funding/Support: This study was funded by Anglogold
PTY (Ltd). Dr Grant is supported by a UK Department of Health Public Health
Career Scientist award. Dr Corbett is supported by a Wellcome Trust Career
Development Fellowship. Dr Chaisson is supported by National Institutes of
Health grant AI01637.
Role of the Sponsor: The funding organization,
Anglogold PTY (Ltd), had no role in the design and conduct of the study; collection,
management, analysis, and interpretation of the data; or preparation, review,
and approval of the manuscript. The funding organization gave permission for
the results to be published at the time the study was commissioned. Anglogold
Health Services PTY (Ltd) participated in the development and implementation
of the clinic and is a subsidiary of Anglogold. At the time of the study,
Aurum Health Research was an independent subsidiary of Anglogold Health Services.
Acknowledgment: We thank the participants;
the staff of Ernest Oppenheimer Hospital, Welkom, South Africa, particularly
those from the TB laboratory, the radiology department, the TB clinic, and
the prevention clinic; and the staff of Aurum Health Research, particularly
Evanne Rothwell, Clement Sefuthi, Themba Moyake, and Edwin Magcuntsu, for
their essential contributions to data collection.