Author Contributions: Dr Holmes had full access
to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design: Holmes, Chen, Kroenke.
Acquisition of data: Holmes, Chen.
Analysis and interpretation of data: Holmes,
Chen, Feskanich, Kroenke, Colditz.
Drafting of the manuscript: Holmes, Colditz.
Critical revision of the manuscript for important
intellectual content: Chen, Feskanich, Kroenke.
Statistical analysis: Holmes, Feskanich.
Obtained funding: Holmes, Chen.
Administrative, technical, or material support:
Financial Disclosures: None reported.
Funding/Support: The research for this article
was funded by grant CA87969 from the National Institutes of Health.
Role of the Sponsor: The National Institutes
of Health had no role in the design and conduct of the study; collection,
management, analysis, and interpretation of the data; and preparation, review,
or approval of the manuscript.
Acknowledgment: We acknowledge the invaluable
programming assistance of Lisa Li, MD.