Author Contributions: Dr Egozcue had full access
to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design; analysis and interpretation
of data: de la Chica, Giraldo, Egozcue, Fuster.
Acquisition of data: Ribas.
Drafting of the manuscript: de la Chica, Ribas,
Giraldo, Egozcue, Fuster.
Critical revision of the manuscript for important
intellectual content; study supervision: Giraldo, Egozcue, Fuster.
Statistical analysis: Giraldo.
Obtained funding: Fuster.
Administrative, technical, or material support:
de la Chica, Ribas.
Financial Disclosures: None reported.
Funding/Support: Financial support for this
study was provided by the Comissionat per a Universitats i Recerca (2001,
Role of the Sponsor: The Comissionat per a
Universitats i Recerca was not involved in the design and conduct of the study;
in the collection, analysis, and interpretation of the data; or in the preparation,
review, or approval of the manuscript.
Previous Presentation: Preliminary results
of this study were presented at the Third European Cytogenetics Conference;
July 7-10, 2001; Paris, France.
Acknowledgment: We thank the Department of
Obstetrics and Gynecology, Institut Universitari Dexeus and the Centro de
Patología Celular for their kind collaboration in providing the samples.