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Ribavirin and Use of Clotting Factors in Patients With Hemophilia and Chronic Hepatitis C

Takashi Honda, MD, PhD; Hidenori Toyoda, MD, PhD; Kazuhiko Hayashi, MD, PhD; Yoshiaki Katano, MD, PhD; Motoyoshi Yano, MD, PhD; Isao Nakano, MD, PhD; Kentaro Yoshioka, MD, PhD; Hidemi Goto, MD, PhD; Koji Yamamoto, MD, PhD; Junki Takamatsu, MD, PhD
JAMA. 2005;293(10):1187-1192. doi:10.1001/jama.293.10.1190-c.
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Figure. Use of Clotting Factor Concentrates 6 Months Before, During, and 6 Months After Combination Therapy With Ribavirin and Interferon for the 5 Patients Requiring Clotting Factor During the Study
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Differences in each period were analyzed by paired t test. P = .03 for comparison of pretreatment and active treatment; P = .06 for comparison of pretreatment and posttreatment. Large data markers indicate mean clotting factor use; error bars, SEs.



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