Author Contributions: Dr Wu had full access
to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design: Croen, Backstrand,
Ferriero, Fullerton, Wu.
Acquisition of data: Lee, Croen, Backstrand,
Yoshida, Henning, Lindan, Barkovich, Wu.
Analysis and interpretation of data: Lee, Croen,
Backstrand, Ferriero, Wu.
Drafting of the manuscript: Lee, Backstrand,
Critical revision of the manuscript for important
intellectual content: Croen, Backstrand, Yoshida, Lindan, Ferriero,
Fullerton, Barkovich, Wu.
Statistical analysis: Lee, Wu.
Obtained funding: Ferriero, Wu.
Administrative, technical, or material support:
Lee, Croen, Yoshida, Henning, Wu.
Study supervision: Croen, Barkovich, Wu.
Financial Disclosures: None reported.
Funding/Support: This study was funded by the
United Cerebral Palsy Foundation. Dr Wu was supported in part by NS35902 from
the National Institutes of Health and the National Institute of Neurological
Disorders and Stroke, and Ms Lee was supported by the Doris Duke Clinical
Research Training Program.
Role of the Sponsor: The United Cerebral Palsy
Foundation had no role in the design and conduct of the study; collection,
management, analysis, and interpretation of the data; or in the preparation,
review, or approval of the manuscript.
Acknowledgment: We thank Carla Stelling, BS,
Roxana Odouli, MSPH, Rick Riordan, BS, and Kim Detels for their research assistance,
as well as Karin Nelson, MD, S. Claiborne Johnston, MD, PhD, and Thomas B.
Newman, MD, MPH, for their mentorship and careful reviews of the manuscript.