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Editorial |

Malignant Gliomas in 2005:  Where to GO From Here?

Paul Graham Fisher, MD; Patricia A. Buffler, PhD
JAMA. 2005;293(5):615-617. doi:10.1001/jama.293.5.615.
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Brain tumor is one of the diagnoses most feared by patients, physicians, and even oncologists. Their fear is justified. More than half of the 18 400 primary malignant brain tumors diagnosed each year in the United States are malignant gliomas1 that not only confer high risk for death and severe disability, but also steal what is held so highly as the essence of human life: the mind and spirit. In this issue of JAMA, Chang et al2 use data from the Glioma Outcomes (GO) Project to provide a “report card” on the patterns of care in patients with newly diagnosed malignant gliomas; unfortunately, the grades are sobering. Consequently, this is an appropriate time to reflect on the past and current status of glioma treatment and suggest where to go from here.

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