Some investigators have reported an association of large body size with
an increased risk of kidney stones, but the specific contributions of weight,
weight gain, and body mass index (BMI) have not been described. Taylor and
colleagues assessed the relationship of body size—reflected in weight,
weight change, BMI, and waist circumference—to incident symptomatic
kidney stones in participants in 3 large prospective studies of health professionals.
After adjusting for age, dietary factors, fluid intake, and thiazide use,
they found that obesity, weight gain since early adulthood, and higher waist
circumference were associated with an increased risk of incident kidney stones.
In analyses by sex, they found the magnitude of risk may be greater in women