Financial Disclosures: Dr Psaty has received
honoraria from Celera Diagnostics. Dr Black has served as a consultant for
Astra-Zeneca, Biovail, Bristol-Myers Squibb, Merck Sharp & Dohme, Novartis,
and Pfizer and has served on the speakers bureau for Astra-Zeneca, Merck Sharp
& Dohme, Novartis, and Pfizer.
Author Contributions: Dr Wassertheil-Smoller
had full access to all of the data in the study and takes responsibility for
the integrity of the data and the accuracy of the data analyses.
Study concept and design: Wassertheil-Smoller,
Psaty, Greenland, Mouton, Trevisan.
Acquisition of data: Wassertheil-Smoller, Greenland,
Oberman, Kotchen, Black, Trevisan.
Analysis and interpretation of data: Wassertheil-Smoller,
Psaty, Greenland, Oberman, Kotchen, Black, Aragaki, Trevisan.
Drafting of the manuscript: Wassertheil-Smoller,
Oberman, Black, Aragaki, Trevisan.
Critical revision of the manuscript for important
intellectual content: Wassertheil-Smoller, Psaty, Greenland, Oberman,
Kotchen, Mouton, Black, Aragaki, Trevisan.
Statistical analysis: Psaty, Aragaki.
Obtained funding: Wassertheil-Smoller, Oberman,
Administrative, technical, or material support:
Study supervision: Wassertheil-Smoller, Oberman,
Women’s Health Initiative Program Office:National Heart, Lung, and Blood Institute, Bethesda, Md:
Barbara Alving, Jacques Rossouw, Linda Pottern.
Clinical Coordinating Center:Fred Hutchinson Cancer Research Center, Seattle, Wash: Ross Prentice,
Garnet Anderson, Andrea LaCroix, Ruth E. Patterson, Anne McTiernan; Wake Forest University School of Medicine, Winston-Salem, NC:
Sally Shumaker, Pentti Rautaharju; Medical Research Labs,
Highland Heights, Ky: Evan Stein; University of California,
San Francisco: Steven Cummings; University of Minnesota,
Minneapolis: John Himes; University of Washington,
Seattle: Bruce Psaty.
Clinical Centers and Investigators:Albert Einstein College of Medicine, Bronx, NY: Sylvia Wassertheil-Smoller; Baylor College of Medicine, Houston, Tex: Jennifer Hays; Brigham and Women's Hospital, Harvard Medical School, Boston,
Mass: JoAnn Manson; Brown University, Providence,
RI: Annlouise R. Assaf; Emory University, Atlanta,
Ga: Lawrence Phillips; Fred Hutchinson Cancer Research
Center, Seattle, Wash: Shirley A. A. Beresford; George Washington University Medical Center, Washington, DC: Judith
Hsia; Harbor-UCLA Research and Education Institute, Torrance,
Calif: Rowan Chlebowski; Kaiser Permanente Center
for Health Research, Portland, Ore: Evelyn Whitlock; Kaiser Permanente Division of Research, Oakland, Calif: Bette Caan; Medical College of Wisconsin, Milwaukee: Jane Morley Kotchen; MedStar Research Institute/Howard University, Washington, DC:
Barbara V. Howard; Northwestern University, Chicago/Evanston,
Ill: Linda Van Horn; Rush-Presbyterian St Luke's
Medical Center, Chicago, Ill: Henry Black; Stanford
Center for Research in Disease Prevention, Stanford University, Stanford,
Calif: Marcia L. Stefanick; State University of New
York, Stony Brook: Dorothy Lane; The Ohio State University,
Columbus: Rebecca Jackson; University of Alabama,
Birmingham: Cora Beth Lewis; University of Arizona,
Tucson/Phoenix: Tamsen Bassford; State University
of New York, Buffalo: Jean Wactawski-Wende; University
of California at Davis, Sacramento: John Robbins; University of California at Irvine, Orange: Allan Hubbell; University of California, Los Angeles: Howard Judd; University of California at San Diego, LaJolla/Chula Vista: Robert
D. Langer; University of Cincinnati, Cincinnati, Ohio:
Margery Gass; University of Florida, Gainesville/Jacksonville: Marian Limacher; University of Hawaii, Honolulu: David Curb; University of Iowa, Iowa City/Davenport: Robert Wallace; University of Massachusetts/Fallon
Clinic, Worcester: Judith Ockene; University of Medicine
and Dentistry of New Jersey, Newark: Norman Lasser; University of Miami, Miami, Fla: Mary Jo O’Sullivan; University of Minnesota, Minneapolis: Karen L. Margolis; University of Nevada, Reno: Robert Brunner; University
of North Carolina, Chapel Hill: Gerardo Heiss; University
of Pittsburgh, Pittsburgh, Pa: Lewis Kuller; University
of Tennessee, Memphis: Karen C. Johnson; University
of Texas Health Science Center, San Antonio: Robert Brzyski; University of Wisconsin, Madison: Gloria Sarto; Wake Forest University School of Medicine, Winston-Salem, NC: Denise
Bonds; Wayne State University School of Medicine/Hutzel
Hospital, Detroit, Mich: Susan Hendrix.
Funding/Support: The Women’s Health Initiative
(WHI) program is funded by the National Heart, Lung, and Blood Institute (NHLBI).
Role of the Sponsor: The NHLBI participated
in the design, conduct, and oversight of the WHI and reviewed this report.
One NHLBI representative serves as a member of the WHI Steering Committee.