Academic and industrial scientists have sharply increased their demand
for properly prepared and clinically annotated tissue samples that yield valuable
insights into the origins and expressions of human disease. Historically,
research on human tissue samples has been relatively unencumbered by federal
regulations and occurred without delineation of ownership rights to the specimens,
patient data, or research products. As regulations have become increasingly
restrictive, and because clear ownership interests have never been established,
the presumed right of researchers and institutions to collect, use, and dispose
of specimens and their associated patient data has remained undefined and
occasionally contentious. Recent examination of these issues by a US federal
court resulted in a ruling that individuals do not retain rights of ownership
or control of biological materials contributed for research, regardless of
whether commercial benefit accrues. This article examines the legal, regulatory,
and ethical framework within which human tissue research is currently conducted.
We contend that because the benefits of medical knowledge derived from tissue
research potentially accrue to all individuals and future generations (rather
than a single recipient), society may justify an expansive use of these valuable
resources for future studies.
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 36
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
and access these and other features:
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.