Author Contributions: Dr McDonald had full
access to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design: McDonald, Dexter,
Acquisition of data: Dexter.
Analysis and interpretation of data: Dexter,
Perkins, McDonald, Maharry.
Drafting of the manuscript: Dexter, McDonald,
Critical revision of the manuscript for important
intellectual content: McDonald, Dexter, Perkins, Jones.
Statistical analysis: Perkins, Maharry, Dexter,
Obtained funding: McDonald.
Administrative, technical, or material support:
McDonald, Dexter, Jones.
Study supervision: Dexter.
Funding/Support:This work was supported in
part by grant HS07719 from the Agency for Healthcare Research and Quality,
as well as contracts N01-LM-6-3546 and N01-LM-9-3542 from the National Library
of Medicine, in part from the Regenstrief Foundation, and the Indiana Genomics
Initiative of Indiana University, which is supported in part by Lilly Endowment
Role of the Sponsors: The funding organizations
are federal agencies or nonprofit foundations. None had a role in the design
or conduct of the study. The required guidelines in the conduct of the study
from the National Institutes of Health were followed. The funding agencies
had no role in the collection, management, analysis, interpretation of the
data, or the preparation of the manuscipt. These agencies neither reviewed
nor approved the manuscript at any time.
Acknowledgment: We are indebted to the nurses,
physicians, students, and administration of Wishard Memorial Hospital, Indianapolis,
Ind, for their efforts and patience.