Author Contributions: Dr Yaffe had full access
to all of the data in the study and takes responsibility for the integrity
of the data and the accuracy of the data analysis.
Study concept and design: Yaffe, Tylavsky,
Acquisition of data: Simonsick, Harris, Tylavsky,
Analysis and interpretation of data: Yaffe,
Kanaya, Lindquist, Simonsick, Shorr, Tylavsky.
Drafting of the manuscript: Yaffe, Shorr.
Critical revision of the manuscript for important
intellectual content: Kanaya, Lindquist, Simonsick, Harris, Shorr,
Statistical analysis: Yaffe, Lindquist.
Obtained funding: Harris, Newman.
Administrative, technical, or material support:
Yaffe, Simonsick, Harris, Tylavsky, Newman.
Study supervision: Kanaya.
Funding/Support: This work was supported by
NIH grants NIA NO1-AG-6-2101, N01-AG-2103, and N01-AG-2106. Dr Yaffe is supported
by the Paul Beeson Faculty Scholars Program, The Mt Zion/UCSF Women’s
Health Grant, and NIH grant NIA-R01 AG021918-01.
Role of the Sponsor: In their role as coauthors,
representatives of the NIH participated in the design and conduct of the study,
in the collection, analysis, and interpretation of the data, and in the preparation,
review, and approval of the manuscript.