The number of persons with coronary artery disease (CAD) is increasing
dramatically, with more patients surviving myocardial infarction (MI), the
aging of the population, and the increasing prevalence of diabetes, obesity,
and inactivity.1 As a result, deaths from cardiovascular
disease have increased about 2.5% per year over the past decade.2 Yet
there is a paucity of prospective randomized trial data on the relative impact
of various drugs and blood pressure levels on adverse outcomes in patients
with CAD. This information is critical to current management of these patients
for many reasons. Past experiences have demonstrated that patients with myocardial
ischemia may react differently to many drugs that otherwise appear safe (eg,
nifedipine, phosphodiesterase inhibitors, antiarrhythmic agents, rofecoxib)
and reducing blood pressure in patients with CAD is very complex. To this
end, 2 large randomized clinical trials3,4 examining
blood pressure treatment in patients with CAD provide important new information
on this issue.
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 11
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
and access these and other features:
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.