Over the last half-century, it has become well recognized that patients
with cardiovascular diseases and, more specifically, ischemic heart disease
may be adversely affected by anemia. This is because the myocardium consumes
or extracts 60% to 75% of all oxygen delivered to the coronary circulation.1- 3 Such an elevated extraction
of oxygen, termed extraction ratio, is unique to the coronary circulation.
As a result, oxygen delivery to the myocardium can be augmented only by increasing
blood flow or oxygen content.1
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