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Incidence of HIV Superinfection Following Primary Infection

Davey M. Smith, MD; Joseph K. Wong, MD; George K. Hightower, BA; Caroline C. Ignacio, BS; Kersten K. Koelsch, MD; Eric S. Daar, MD; Douglas D. Richman, MD; Susan J. Little, MD
JAMA. 2004;292(10):1177-1178. doi:10.1001/jama.292.10.1177.
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Figure. Phylogram of 15-20 Clonal Sequences of the V3 Coding Region of env From Both Time-Point Samples From Each Individual Suspected of Being Superinfected
Graphic Jump Location
Circles indicate 3 individuals (A, B, and C) suspected of being superinfected, each with 2 isolates. Clonal sequences are clustered by time-point sample but not by individual. There was no intermingling of clonal sequences between time points, and sequence clusters differed by >8% homology and were separated by epidemiologically unrelated strains from 15 individuals in San Diego and Los Angeles (unlabeled branches) and laboratory strains (labeled branches).



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