0
Editorial |

Do Tumors Detected by Mammography Screening Have a Favorable Prognosis?

Ruth M. O'Regan, MD
JAMA. 2004;292(9):1062-1063. doi:10.1001/jama.292.9.1062.
Text Size: A A A
Published online

Extract

Considerable progress has been made in the last 20 years in improving outcomes for patients with breast cancer because of earlier detection and application of more effective therapies. The use of tamoxifen reduces the risk of recurrence and improves survival in patients with early stage hormone receptor–positive breast cancer.1 Recent evidence suggests that adjuvant use of aromatase inhibitors may further add to the benefits seen with tamoxifen.24 Likewise, the use of adjuvant chemotherapy has been demonstrated to reduce recurrence and mortality in patients with early stage breast cancer, particularly in younger patients and in those with tumors that do not express hormone receptors.5 Nonetheless, many patients would remain free of cancer following local therapy (surgery with or without radiotherapy) with no adjuvant systemic hormonal or chemotherapy. Much research is currently focused on tailoring the use of adjuvant systemic therapies and on identifying patients with tumor characteristics associated with a favorable prognosis.

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 3

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...
Articles Related By Topic
Related Topics
PubMed Articles
Jobs
JAMAevidence.com

The Rational Clinical Examination
Effectiveness of CBE

The Rational Clinical Examination
Table 8-7 Mammography Screening Is Increasing as Clinical Breast Examination Is Decreasing

brightcove.createExperiences();