Lung cancer is a worldwide epidemic primarily caused by tobacco smoking.1 Approximately 1 million new cases of lung cancer are
diagnosed each year worldwide, resulting in more than 900 000 deaths.2 Of these, approximately 175 000 new cases and
160 000 deaths occur annually in the United States.3 Unfortunately,
late diagnosis of lung cancer is the rule, and no curative therapies exist
for metastatic disease. Nevertheless, perceptible progress in the treatment
of this disease has been made as the result of painstaking efforts and decades
of clinical investigations.
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