Patent Application: In the Original Contribution
entitled "Association Between Estrogen Receptor α Gene Variation and
Cardiovascular Disease" published in the November 5, 2003, issue of THE JOURNAL
(2003;290:2263-2270), a provisional patent application was filed after the
article went to press. The patent application for medical uses related to
the ESR1 c.454-397T>C polymorphism was filed through
the Massachusetts Institute of Technology's Technology Licensing Office on
behalf of Drs Housman, Levy, Mendelsohn, and Shearman.