In 1937 US Surgeon General Thomas Parran estimated that 10% of Americans
would be infected with syphilis during their lives.1 Rates
of primary and secondary syphilis plummeted with the institution of public
health control measures and the advent of penicillin, reaching a nadir in
2000. Since then, rates have continued to decline among women and infants,
although overall rates again have begun to climb.2
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