Pediatricians and other child health professionals routinely treat children
with medications that have not been proven to be safe and effective for their
patient population and that have labels that lack appropriate guidance from
the manufacturer on how those drugs should be used for children. Shocking?
Perhaps. But in reality those who provide medical care to children have little
choice because, as noted in the article by Roberts et al1 in
this issue of THE JOURNAL, "only one third of drugs used to treat children
have been studied adequately in the population in which they are being used
and have appropriate use information on the product label. For the other two
thirds of drugs, information regarding safety and efficacy for pediatric patients
is insufficient or absent."
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