Conventional wisdom (or misconception) holds that the 4 major modifiable
traditional cardiovascular risk factors—smoking, diabetes mellitus,
hypertension, and hypercholesterolemia—account for "only 50%" of those
who go on to develop coronary heart disease (CHD),1,2 even
though the original source of this claim is not well documented. Thus, over
the past decade, a search to discover novel markers and other nontraditional
risk factors to assess cardiovascular risk has come to the forefront.
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The Rational Clinical Examination
About 16% of general medical patients report that they have palpitations.1 Within...
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