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Editorial |

Combining Resynchronization and Defibrillation Therapies for Heart Failure

David J. Bradley, MD, PhD
JAMA. 2003;289(20):2719-2721. doi:10.1001/jama.289.20.2719.
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Despite major advances in pharmacological therapy during the past 2 decades,1,2 heart failure is associated with more than 280 000 deaths annually in the United States.3 The most common modes of death among patients with symptomatic heart failure are sudden cardiac death and death from progressive heart failure.2 Two classes of implantable cardiac devices, implantable cardioverter defibrillators (ICDs) and cardiac resynchronization devices, separately address these modes of death in heart failure. Implantable cardioverter defibrillators can terminate potentially lethal ventricular arrhythmias by pacing or shocking the heart. In high-risk patients, ICDs reduce sudden cardiac death by 57% relative to usual care and improve overall survival.4 Implantable cardioverter defibrillators, however, generally do not improve quality of life.5

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The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
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