The lifetime prevalence of headache is more than 90%.1 In
recent population-based surveys of US adults, nearly 25% annually report recurrent
episodes of severe headache and 4% daily or near-daily headache.2- 4 Prescription
or nonprescription products are used by 9% of US adults each week to treat
headache, matching hypertension as the primary reason for medication use.5 The majority of patients presenting to physicians
will have primary headache syndromes such as tension-type, cluster, and migraine.
Less than 2% of patients in office and 4% of patients in emergency department
settings will be found to have headaches secondary to significant pathology.6
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