The doubling of the National Institutes of Health (NIH) budget in recent
years,1,2 the publication of the
initial sequence and analysis of the human genome in 2001,3,4 and
advances in molecular biology, neuroscience, immunology, biomedical engineering,
and functional magnetic resonance imaging suggest that these remarkable achievements
in clinical and basic science research are being successfully translated to
the clinic and bedside. There is an assumption that the recent exponential
growth of scientific information about disease, as evidenced by the substantial
increase in the numbers of published articles in biomedical journals, heralds
a rapid move to improve human health.
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