0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Contempo Updates |

Current and Emerging Infectious Risks of Blood Transfusions

Michael P. Busch, MD, PhD; Steven H. Kleinman, MD; George J. Nemo, PhD
JAMA. 2003;289(8):959-962. doi:10.1001/jama.289.8.959.
Text Size: A A A
Published online

Extract

The blood supply in the United States and other developed countries has never been as safe as it is now. During the past several decades, there have been dramatic progressive reductions in the risk of transfusion-transmitted clinically significant blood-borne infections. This has been accomplished as a result of extensive research to characterize transfusion-transmitted pathogens, development of strategies to measure infection rates in blood donor and recipient populations, characterization of the dynamics of early viremia, and implementation of progressively more restrictive donor eligibility criteria and increasingly sensitive laboratory screening methods.

Figures in this Article

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Figure. Decline in Human Immunodeficiency Virus (HIV) and Hepatitis B (HBV) and Hepatitis C (HCV) Risks of Transmission Through Transfusion
Graphic Jump Location
Data were derived from studies sponsored by the National Heart, Lung, and Blood Institute. Specific references are available from the authors upon request. Estimates before 1991 are based on donor prevalence measurements (black data markers) or recipient follow-up studies (gray data markers); estimates after 1991 represent projections based on mathematical modeling (open data markers). Estimated risk of infection per unit transfused in 2000-2001 was 1:220 000 for HBV; 1:1 600 000 for HCV; and 1:1 800 000 for HIV.

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Web of Science® Times Cited: 153

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();