Contrast nephropathy is one of the well-recognized risks of coronary
angiography. Although the disease occurs infrequently with normal renal function,
its frequency increases with decreasing renal function, ranging from 5% in
patients with mild renal insufficiency1 to
50% in those with severe renal dysfunction and diabetes.2 Given
that contrast nephropathy is associated with increased morbidity, mortality,
and length of hospitalization, and possibly with long-term renal impairment,3 there is great interest in its prevention.
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