Polyarteritis nodosa (PAN) is regarded rightly as the grandfather of
the vasculitides. In this Grand Rounds, the case of a 30-year-old man with
a 12-year illness is described. The patient presented with daily fevers, tachycardia,
and cutaneous ulcers on his distal extremities. He eventually developed mononeuritis
multiplex. Because of the striking pattern of his fevers, he was diagnosed
for many years as having adult-onset Still disease. Following the addition
of daily cyclophosphamide to his long-standing regimen of prednisone, the
patient's disease entered remission for the first time in more than a decade.
He was ultimately able to discontinue all of his immunosuppressive medications.
The case is discussed in the context of the first patient ever described with
PAN, the classic report of Kussmaul and Maier.
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 27
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
and access these and other features:
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.