San Francisco—Analysis of the genetic mutations behind the transformation and growth of cancer cells provides information that is spurring the development of new and better ways to diagnose and treat cancer. But many researchers are also looking beyond the "blueprint for life" to proteins for insights the genome does not provide.
Proteomics, which includes analysis of protein interactions in a cell (JAMA. 2001;286:2211-2214), is a young field but one that is growing fast. By cataloging the many proteins in the body and discovering how they function in tissues, researchers hope to gain a better understanding of what goes wrong in the protein networks in cancer cells.
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