0
Quick Uptakes |

Depression and MI Deaths

Mike Mitka
JAMA. 2001;286(20):2534. doi:10.1001/jama.286.20.2534.
Text Size: A A A
Published online

Extract

Researchers at Washington University School of Medicine, St Louis, may have found the reason that depression in patients who have had a myocardial infarction (MI) increases the risk of death. The findings appear in the October 23 issue of Circulation: Journal of the American Heart Association.

The investigators studied a subset of participants in the Enhancing Recovery in Coronary Heart Disease (ENRICHED) clinical trial of patients admitted to coronary care units between 1997 and 2000. Using criteria in the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, 307 patients with MI were diagnosed as having major or minor depression and 366 as having neither. All had had an MI in the 28 days before joining the trial. Each underwent 24-hour ambulatory electrocardiographic monitoring after hospital discharge to assess heart rate variability (HRV), a measure of cardiac autonomic function, including sympathetic and parasympathetic nervous systems. Low HRV reflects excessive sympathetic or reduced parasympathetic function and is a strong independent predictor of post-MI death.

Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
/>
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Topics
PubMed Articles
Jobs
JAMAevidence.com

The Rational Clinical Examination
Make the Diagnosis: Depression

The Rational Clinical Examination
Original Article: Is This Patient Clinically Depressed?

brightcove.createExperiences();