0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
This Week in JAMA |

This Week in JAMA FREE

JAMA. 2001;285(11):1399. doi:10.1001/jama.285.11.1399.
Text Size: A A A
Published online

WOMEN'S HEALTH

Edited by Catherine D. DeAngelis, MD, MPH, and Margaret A. Winker, MD

PHYSICAL ACTIVITY AND CORONARY HEART DISEASE IN WOMEN

Physically active women have lower rates of coronary heart disease than inactive women. To determine whether this association differs by intensity of activity or for women at high risk of coronary heart disease, Lee and colleagues analyzed data from 39 372 healthy women enrolled in the Women's Health Study and followed up for an average of 5 years. Physical activity, even light to moderate activity, was inversely associated with risk of coronary heart disease, including among women who were overweight, had increased cholesterol levels, or were smokers.

See Article

HOMICIDE AS A CAUSE OF PREGNANCY-ASSOCIATED DEATH

Using a definition of pregnancy-associated death as a death during pregnancy or within 1 year of delivery or pregnancy termination from any cause, including injuries, suicide, or homicide, Horon and ChengArticle used multiple data sources to identify pregnancy-associated deaths in Maryland between 1993 and 1998. The leading cause of pregnancy-associated death was homicide, followed by cardiovascular disorders. In an editorial, FryeArticle urges routine screening of all female patients for domestic violence.

ESTROGEN AFTER MENOPAUSE

The decision to use hormone replacement therapy (HRT) after menopause is complicated by conflicting data on its benefits, such as reducing risk of dementia, and the increase in risk of endometrial and breast cancer, and possibly ovarian cancer. In a prospective study of postmenopausal women followed up for 14 years, Rodriguez and colleaguesArticle found that women who used estrogens at baseline (1982) or within 15 years prior to baseline for 10 or more years had higher death rates from ovarian cancer than never users. Geerlings and colleaguesArticle, using data from a prospective study of postmenopausal women aged 55 or older, found that a longer reproductive period, as an indicator of long-term exposure to endogenous estrogens, was not associated with a decreased risk of dementia. LeBlanc and colleaguesArticle conducted a systematic review and meta-analysis of studies on the relationship between HRT and the risk of cognitive decline and dementia. HRT use was associated with improvement in some cognitive functions among women who had symptoms of menopause, but not among asymptomatic women. Risk of dementia appeared to be reduced among women who used HRT, but most of the studies had methodological limitations.

MORTALITY AMONG WOMEN WITH HIV AND DEPRESSION

Clinical levels of depression have been reported by 30% to 60% of women infected with HIV. Ickovics and colleagues used data from the prospective HIV Epidemiologic Research Study to determine whether depressive symptoms were associated with HIV-related mortality among women infected with HIV observed for up to 7 years. HIV-seropositive women with chronic depressive symptoms were 2 times more likely to die than those with limited or no depressive symptoms. Chronic depressive symptoms were also associated with significantly greater decline in CD4 cell counts.

See Article

IPRIFLAVONE AS THERAPY FOR POSTMENOPAUSAL OSTEOPOROSIS

In preclinical studies, ipriflavone, a synthetic isoflavone derivative available as an over-the-counter preparation, has been shown to inhibit bone resorption and stimulate osteoblast activity. In this randomized trial among postmenopausal women, Alexandersen and colleagues found that during the 3-year treatment period, decreases in bone mineral density were not significantly different between the ipriflavone and placebo groups, and changes in biochemical markers of bone resorption and rates of new vertebral fracture were also similar. Twenty-nine of the 234 women in the ipriflavone group developed subclinical lymphocytopenia during ipriflavone treatment, most of whom recovered spontaneously within 2 years after discontinuation of ipriflavone.

See Article

A PIECE OF MY MIND

"When I was told my diagnosis, my first question was: ‘How will I tell my sisters?'" From "Searching for Margaret."

See Article

CONTEMPO UPDATES

Available therapies for postmenopausal osteoporosis and the patient subgroups likely to benefit.

See Article

MEDICAL NEWS & PERSPECTIVES

Physicians who treat women are putting increased emphasis on encouraging physical exercise to enhance female strength and agility and on effectively treating depression.

See Article

CERVICAL CYTOLOGIC AND HISTOLOGIC DIAGNOSES

Findings that agreement among well-trained pathologists on the interpretation of cytologic and histologic cervical specimens is only moderate, and not more reproducible for histologic than for cytologic specimens, underscore the need to clarify diagnostic criteria and nomenclature.

JAMA PATIENT PAGE

For your patients: Information about the benefits of physical activity and exercise for women's cardiovascular health.

See Article

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Related Content

Customize your page view by dragging & repositioning the boxes below.