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Medical News & Perspectives |

Helsinki Discord? A Controversial Declaration

Brian Vastag
JAMA. 2000;284(23):2983-2985. doi:10.1001/jama.284.23.2983.
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Washington—A long-awaited fifth revision of the Declaration of Helsinki, widely acknowledged as the foundation of medical research ethics, is receiving mixed reactions for discouraging placebos in clinical trials and mandating researchers to provide "best proven" therapy to participants after a trial.

Patient protection advocates, who lobbied hard for the new language, hail the revision as a major step toward abolishing what they see as unethical research, especially in developing nations. Delon Human, MD, secretary general of the World Medical Association (WMA), which put forth the declaration, is equally enthusiastic. He says the revision is an ideal—not a "manual of protocols and procedures"—but that it sets an ethical standard "which I don't think can be set high enough."

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