Editorial |

Toward Evidence-Based Management of Migraine

David B. Matchar, MD; Douglas C. McCrory, MD, MHSc; Rebecca N. Gray, DPhil
JAMA. 2000;284(20):2640-2641. doi:10.1001/jama.284.20.2640.
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Migraine has long been recognized as a painful and debilitating disorder that profoundly affects the lives of individuals and their families. Population studies conducted over the past decade paint a startling picture of migraine as a major public health problem, suggesting that nearly 1 in 5 women and 1 in 20 men have disabling migraine.1,2 While precise estimates vary, migraine is clearly responsible for millions of bedridden and reduced-activity days per year and billions of dollars in medical costs and lost productivity.24 Yet most people with migraine are never diagnosed by a physician or treated with prescription medication,1,5,6 and those who do receive care are frequently dissatisfied with the results.7

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