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JAMA Clinical Guidelines Synopsis |

Use of HPV Vaccine in Males and Females

Adam S. Cifu, MD1; Andrew M. Davis, MD, MPH2
[+] Author Affiliations
1Department of Medicine, University of Chicago
2Section of General Internal Medicine, University of Chicago, Chicago, Illinois
JAMA. 2014;312(18):1920-1921. doi:10.1001/jama.2014.12274.
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Guideline title Human Papillomavirus (HPV) ACIP Vaccine Recommendations

Developer Advisory Committee for Immunization Practices (ACIP)

Release date August 29, 2014

Prior version May 28, 2010

Funding source US Department of Health and Human Services (DHHS)

Target population Girls and women aged 11-26 years; boys and men aged 11-21 years

Major Recommendations

  • HPV vaccination (either bivalent or quadrivalent) should be administered to girls aged 11-12 years.

  • Girls and women aged 13-26 years who have not started or completed the vaccine series should be vaccinated.

  • Quadrivalent HPV vaccination should be administered to boys aged 11 or 12 years.

  • Boys and men aged 13-21 years who have not been vaccinated previously or who have not completed the 3-dose series should also receive the quadrivalent vaccine. Males aged 22-26 years may be vaccinated.

  • Either vaccine can be administered to those as young as 9 years of age.

  • Quadrivalent HPV vaccination is also recommended for men who have sex with men and immunocompromised persons up to 26 years.

  • The vaccine is administered in a 3-dose schedule. The second dose should be administered 1 to 2 months after the first dose and the third dose should be administered 6 months after the first dose.

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