This series provides clinicians with strategies and tools to interpret
and integrate evidence from published research in their care of patients.
The 2 key principles for applying all the articles in this series to patient
care relate to the value-laden nature of clinical decisions and to the hierarchy
of evidence postulated by evidence-based medicine. Clinicians need to be able
to distinguish high from low quality in primary studies, systematic reviews,
practice guidelines, and other integrative research focused on management
recommendations. An evidence-based practitioner must also understand the patient's
circumstances or predicament; identify knowledge gaps and frame questions
to fill those gaps; conduct an efficient literature search; critically appraise
the research evidence; and apply that evidence to patient care. However, treatment
judgments often reflect clinician or societal values concerning whether intervention
benefits are worth the cost. Many unanswered questions concerning how to elicit
preferences and how to incorporate them in clinical encounters constitute
an enormously challenging frontier for evidence-based medicine. Time limitation
remains the biggest obstacle to evidence-based practice but clinicians should
seek evidence from as high in the appropriate hierarchy of evidence as possible,
and every clinical decision should be geared toward the particular circumstances
of the patient.
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Country-Specific Mortality and Growth Failure in Infancy and Yound Children and
Association With Material Stature
Use interactive graphics and maps to view and sort country-specific infant and early
dhildhood mortality and growth failure data and their association with maternal
Thank you for submitting a comment on this article. It will be reviewed by JAMA editors. You will be notified when your comment has been published. Comments should not exceed 500 words of text and 10 references.
Do not submit personal medical questions or information that could identify a specific patient, questions about a particular case, or general inquiries to an author. Only content that has not been published, posted, or submitted elsewhere should be submitted. By submitting this Comment, you and any coauthors transfer copyright to the journal if your Comment is posted.
* = Required Field
Disclosure of Any Conflicts of Interest*
Indicate all relevant conflicts of interest of each author below, including all relevant financial interests, activities, and relationships within the past 3 years including, but not limited to, employment, affiliation, grants or funding, consultancies, honoraria or payment, speakers’ bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued. If all authors have none, check "No potential conflicts or relevant financial interests" in the box below. Please also indicate any funding received in support of this work. The information will be posted with your response.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 271
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Users' Guides to the Medical Literature
Chapter 2. The Philosophy of Evidence-Based Medicine
Users' Guides to the Medical Literature
Chapter 22.6. Parallel but Separate Goals: Evidence-Based Practitioners and Evidence-Based Care
All results at
and access these and other features:
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.