Published Online: October 26, 2014. doi:10.1001/jama.2014.13959.
Study concept and design: J. G. Smith, Thanassoulis.
Acquisition, analysis, or interpretation of data: J. G. Smith, Luk, Schultz, Engert, Do, Hindy, Rukh, Dufresne, Almgren, Owens, Harris, Peloso, Kerr, Wong, A. V. Smith, Budoff, Rotter, Cupples, Rich, Kathiresan, Orho-Melander, Gudnason, Post, Thanassoulis.
Drafting of the manuscript: J. G. Smith, Luk, Thanassoulis.
Critical revision of the manuscript for important intellectual content: J. G. Smith, Schultz, Engert, Do, Hindy, Rukh, Dufresne, Almgren, Owens, Harris, Peloso, Kerr, Wong, A. V. Smith, Budoff, Rotter, Cupples, Rich, Kathiresan, Orho-Melander, Gudnason, O’Donnell, Post, Thanassoulis.
Statistical analysis: J. G. Smith, Luk, Schultz, Engert, Do, Dufresne, Almgren, Peloso, Kerr, A. V. Smith, Cupples, Kathiresan, Thanassoulis.
Obtained funding: J. G. Smith, Harris, Budoff, Rotter, Orho-Melander, Gudnason, O’Donnell, Thanassoulis.
Administrative, technical, or material support: J. G. Smith, Luk, Owens, Harris, Rotter, Rich, Kathiresan, Orho-Melander, Gudnason, Thanassoulis.
Study supervision: J. G. Smith, Thanassoulis.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Cupples reported having received funding from Boston Heart Diagnostics. Dr Thanassoulis reported having received speaker fees from Servier Canada. No other disclosures were reported.
Funding/Support: The Malmö Diet and Cancer study was supported by the Swedish Cancer Society, the Swedish Medical Research Council, the Swedish Dairy Association, the Albert Påhlsson and Gunnar Nilsson Foundations, and the Malmö city council. Dr J. G. Smith was supported by the Swedish Heart-Lung Foundation, governmental funding of clinical research within the Swedish National Health Service, the Crafoord Foundation, Skåne University Hospital, and the Thorsten Westerström Foundation. The Age, Gene/Environment Susceptibility–Reykjavik Study was supported by a grant from the National Institute on Aging (N01-AG-12100) and by the National Eye Institute, the National Institute on Deafness and Other Communication Disorders, the National Heart, Lung, and Blood Institute (NHLBI), the National Institute on Aging Intramural Research Program, Hjartavernd (the Icelandic Heart Association), and the Althingi (Icelandic parliament). The MESA, MESA CARe, and the MESA SHARe project were supported by contracts N01-HC-95159 through 95169, N01-HC-65226, and N02-HL-64278 and grants from the NHLBI (UL1 RR024156, R01-HL-071051, R01-HL-071205, R01-HL-071250, R01-HL-071251, R01-HL-071252, R01-HL-071258, R01-HL-071259). Computed tomographic measures in MESA were supported by a grant to Dr Budoff (R01 HL071739). The Framingham Heart Study was supported by contracts from the NHLBI (N01-HC-25195, N02-HL-64278) with Affymetrix for genotyping services. Dr Kathiresan was supported by the American College of Cardiology Foundation/Merck Adult Cardiology Research Fellowship Award and the GlaxoSmithKline Research and Education Foundation for Cardiovascular Disease Young Investigator Award. Dr Thanassoulis was supported by a Clinician-Scientist Salary Award from the Fonds de la Recherche du Québec–Santé and operating grants from the RI-MUHC/Merck Research Competition and the Canadian Institutes of Health Research (MOP-119380 and MOP-126033).
Role of the Funder/Sponsor: The sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.