We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
From The JAMA Web Sites |

Potential Use of a Caspase Against HIV

Terri H. Finkel, MD PhD
JAMA. 1999;282(11):1021-1022. doi:10.1001/jama.282.11.1021.
Text Size: A A A
Published online


Journal Scan Archive
January 1999
Posted March 19, 1999

Perelson AS, Neumann AU, Markowitz M, Leonard JM, Ho DD.HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time. Science.1996;271:1582-1586.
Wei X, Ghosh SK, Taylor ME.  et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature.1995;373:117-122.
Hellerstein M, Hanley MB, Cesar D.  et al. Directly measured kinetics of circulating T lymphocytes in normal and HIV-1–infected humans. Nat Med.1999;5:83-89.
Finkel TH, Casella CR.AIDS and cell death.In: Zakeri Z, Tilly J, Lockshin RA, eds. Cell Death: Significance and Directions. New York, NY: Wiley-Liss; 1998:289-318.
Finkel TH, Tudor-Williams G, Banda NK.  et al. Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes. Nat Med.1995;1:129-134.
Casella CR, Finkel TH.Mechanisms of lymphocyte killing by HIV. Curr Opin Hematol.1997;4:24-31.
Finzi D, Hermankova M, Pierson T.  et al. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science.1997;278:1295-1300.
Vocero-Akbani AM, Heyden NV, Lissy NA, Ratner L, Dowdy SF.Killing HIV-infected cells by transduction with an HIV protease-activated caspase-3 protein. Nat Med.1999;5:29-33.
Schulz TF, Boshoff CH, Weiss RA.HIV infection and neoplasia. Lancet.1996;348:587-591.


hiv ; caspases

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?




Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
PubMed Articles

Care at the Close of Life: Evidence and Experience
Overcoming the False Dichotomy of Curative vs Palliative Care for Late-Stage HIV/AIDS: "Let Me Live the Way I Want to Live, Until I Can't"

The Rational Clinical Examination: Evidence-Based Clinical Diagnosis
Evidence to Support the Update