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Comment & Response |

Diabetes Prevalence Among Youth

Ryan T. Demmer, PhD, MPH1; Aleksandra M. Zuk, RN, MPH2; Michael Rosenbaum, MD3
[+] Author Affiliations
1Department of Epidemiology, Columbia University, New York, New York
2University of Toronto, Dalla Lana School of Public Health, Toronto, Ontario, Canada
3Department of Pediatrics, Columbia University, New York, New York
JAMA. 2014;312(11):1153. doi:10.1001/jama.2014.9617.
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To the Editor The SEARCH investigators assessed the burden of diagnosed diabetes among youth.1 We wish to discuss 2 important limitations of the SEARCH study design.

First, the SEARCH study design cannot account for undiagnosed type 2 diabetes and therefore underestimates disease burden. The authors acknowledged this limitation but speculated that the number of cases was small based on only 2 specific citations: the first citation was from a geographically homogenous sample and the second was from a sample of sixth graders, thus underestimating the rates among older adolescents.

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May 7, 2014
Dana Dabelea, MD, PhD; Elizabeth J. Mayer-Davis, PhD; Sharon Saydah, PhD; Giuseppina Imperatore, MD; Barbara Linder, MD, PhD; Jasmin Divers, PhD; Ronny Bell, PhD ; Angela Badaru, MD; Jennifer W. Talton, MS; Tessa Crume, PhD; Angela D. Liese, PhD; Anwar T. Merchant, DMD, ScD; Jean M. Lawrence, ScD, MPH, MSSA; Kristi Reynolds, PhD; Lawrence Dolan, MD; Lenna L. Liu, MD, MPH; Richard F. Hamman, MD, DrPH; for the SEARCH for Diabetes in Youth Study
1Department of Epidemiology, Colorado School of Public Health, Aurora
2Department of Nutrition, University of North Carolina, Chapel Hill
3Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia
4Childhood Diabetes Research Division of Diabetes, Endocrinology and Metabolic Diseases, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland
5Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina
6Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, North Carolina
7Department of Pediatric Endocrinology and Diabetes, Children’s Hospital and Regional Medical Center, Seattle, Washington
8Department of Epidemiology and Biostatistics, Arnold School of Public Health, Columbia, South Carolina
9Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena
10Department of Endocrinology, Children's Hospital Medical Center, Cincinnati, Ohio
11Department of Pediatrics, University of Washington, and Seattle Children’s Hospital, Seattle
JAMA. 2014;311(17):1778-1786. doi:10.1001/jama.2014.3201.
September 17, 2014
Dana Dabelea, MD, PhD; Elizabeth J. Mayer-Davis, PhD
1Department of Epidemiology, Colorado School of Public Health, Aurora
2Department of Nutrition, University of North Carolina, Chapel Hill
JAMA. 2014;312(11):1153-1154. doi:10.1001/jama.2014.9620.
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