In the Original Investigation entitled “Effect of Flexible Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality: A Randomized Clinical Trial” published in the August 13, 2014, issue of JAMA (2014;312:606-615. doi:10.1001/jama.2014.8266), several errors appeared. The author affiliations for Drs Eide, Skovlund, and Schneede were incorrect. Also, the title for Figure 4 was duplicative of the title for Figure 3. In addition, the company Falk Pharma was printed incorrectly in the Conflict of Interest Disclosures paragraph. This article was corrected online.