Study concept and design: Udell, Kohli, Roe, Wiviott.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Udell.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Li, Roe.
Obtained funding: Udell, Roe.
Administrative, technical, or material support: Udell, Wang, Kohli, Roe.
Study supervision: Wang, Roe.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Udell reported receiving honoraria from the American College of Cardiology Foundation. Dr Wang reported receiving honoraria from the American College of Cardiology Foundation and AstraZeneca; and research funding to Duke Clinical Research Institute from Lilly USA, Daiichi Sankyo, GlaxoSmithKline, and Gilead Science. Dr Kohli reported serving as a consultant to Live and Jeffries Research. Dr Roe reported receiving grants from Eli Lilly & Company, Daiichi Sankyo, sanofi-aventis, the American College of Cardiology, the American Heart Association, and the Familial Hypercholesterolemia Foundation; and personal fees from Merck, Janssen Pharmaceuticals, Regeneron, AstraZeneca, and Amgen outside the submitted work. Dr de Lemos reported receiving lecture honoraria from AstraZeneca; consulting income from Janssen Pharmaceuticals, Diadexus, St Jude Medical, and Roche Diagnostics; and grant support and consulting income from Roche Diagnostics and Abbott Diagnostics. Dr Wiviott reported receiving grants from Arena, AstraZeneca, Bristol-Myers Squibb, Daiichi Sankyo, Eisai, Eli Lilly, Merck, and sanofi-aventis; and consulting fees from Aegerion, Angelmed, Arena, AstraZeneca, Boston Clinical Research Institute, Bristol-Myers Squibb, Daiichi Sankyo, Eisai, Eli Lilly, ICON Clinical, Janssen, and Xoma. No other disclosures were reported.
Funding/Support: This research was supported by the American College of Cardiology Foundation’s National Cardiovascular Data Registry (NCDR). The Acute Coronary Treatment and Intervention Outcomes Network (ACTION) Registry–Get With The Guidelines (GWTG) is sponsored in part by the partnership between Bristol-Myers Squibb and sanofi pharmaceuticals. Dr Udell was supported in part by a postdoctoral research fellowship from the Canadian Institutes for Health Research and the Canadian Foundation for Women’s Health.
Role of the Sponsors: The study was designed by Drs Udell and Wiviott and approved by the NCDR. The ACTION Registry–GWTG research and publications subcommittee reviewed and approved the proposal and final draft of the manuscript. The funding agency had no role in the conduct of the study; collection, management, analysis, and interpretation of the data; preparation of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: The views expressed in this manuscript represent those of the authors, and do not necessarily represent the official views of the NCDR or its associated professional societies identified at http://www.ncdr.com.
Additional Contributions: We thank Elliott M. Antman, MD (Brigham and Women’s Hospital, Boston, Massachusetts), for review of the manuscript, for which he received no compensation.