Group Information: The Taiwan Severe Cutaneous Adverse Reactions Consortium comprises the physicians, pharmacists, and other investigators from Taipei Medical University Hospital, Wan Fang Hospital, Chung Shan University Hospital, Taichung Veterans General Hospital, Changhua Christian Hospital, China Medicine University Hospital, National Cheng Kung University Hospital, National Taiwan University Hospital, and Chang Gung Memorial Hospitals.
Study concept and design: Chung, Hung.
Acquisition, analysis, or interpretation of data: All authors.
Drafting of the manuscript: Chung, Hung.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Chung, W.-C. Chang, Lee, Shi, Y.-S. Chang, Hung.
Obtained funding: Chung, Hung.
Administrative, technical, or material support: All authors.
Study supervision: Chung, Hung.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Drs Chung and Hung report a patent application pending for risk assessment for phenytoin-induced adverse drug reactions. No other disclosures were reported.
Funding/Support: This work was supported by the National Science Council, Taiwan (grants NSC101-2320-B-010-072-MY3, NSC101-2321-B-010-027, NSC101-2628-B-182-001-MY3, NSC101-2321-B-182-008, and NSC102-2314-B-010-014-MY3), the National Core Facility Program for Biotechnology (Bioinformatics Consortium of Taiwan; grant NSC100-2319-B-010-002) for statistical assistance, and Chang Gung Memorial Hospital (grants OMRPG-2C0011, OMRPG-2C0021, CMRPG-290051-3, and CMRPG-3D0351).
Role of the Sponsors: The study sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; or decision to submit the manuscript for publication.
Additional Contributions: We thank Michiko Aihara, MD, PhD, Department of Dermatology, Yokohama City University, Japan, for cases collection, and Yu-Wei Yang, BS, and Yen-Ling Lin, MS, from the Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, for data management, and members of the Genomic Medicine Research Core Laboratory of Chang Gung Memorial Hospital, and VYM Genome Research Center of National Yang-Ming University, Taiwan, for excellent technical assistance. No compensation was received.